"I had my ovaries and [fallopian] tubes removed", the mother-of-one revealed.
Since the star, who has a six-year-old daughter, is BRCA positive, which means a person is more likely to develop ovarian and breast cancers, she made a decision to have another procedure to decrease her chances of dying from cancer.
Speaking exclusively to Today.com, Applegate said that her cousin died of ovarian cancer in 2008, which led to the realization that she could prevent that from happening to her too.
Applegate also explained how stress can take years off of your life so it's important to try to relax whenever possible. It's a relief. That's one thing off the table. "Now, let's hope I don't get hit by a bus", she joked.
"The chances that my daughter is BRCA positive are high. I'm doing everything I can on my end knowing that in 20 years, she'll have to start getting tested", she told Today.
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The former Up All Night star says that she grows her own vegetables with Sadie and husband Martyn LeNoble to ensure that they're eating clean foods.
"The first thing she said to me is: 'Christina, this is a blessing that's happened to you in your life. It breaks my heart to think that's a possibility", she said.
The surgery decreases women's chances of developing both breast and ovarian cancer, which is the fifth deadliest cancer for women and kills more women than any other gynecologic cancer. My daughter [Sadie, soon 7 years, ed] is a vegetarian, and practically vegan. Still, she decided on the double mastectomy to avoid having to go through the procedure again. That's her choice, ' Applegate said.
Christina Applegate took drastic measures to try to prevent cancer. I work at her school six or seven hours a week.
In parallel to his activities as an actress, Christina Applegate is since 2009 head of the foundation, Right Action For Women, an organization she created and who comes to the aid of women who are carriers of the BRCA gene.