Mourinho guided United to success in the EFL Cup and the Europa League last term and has made an encouraging start in his bid to win the Premier League title this season.
The Reds ace has been ruled out for up to six weeks with a hamstring injury.
He told Premier League Productions: "I don't know how he is".
"An outsider would say that Mourinho would have the right to feel aggrieved should Lukaku start against Cyrpus with Roberto Martinez having more than capable replacements in Chelsea's MIchy Batshuayi and the match having no outcome on Belgium" s World Cup Qualifying campaign.
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And Neville thinks Mane is a pivotal player for Liverpool but the likes of Mohamed Salah, Roberto Firmino and Philippe Coutinho could all step up in his absence. Maybe if we were in a moment of the season where it was a duel between two teams it would mean more but it's not the case.
With Pogba not expected back until November Ander Herrera, who has played a bit-part role so far this season, could be recalled for the crunch game at Anfield.
"Now he is 100 per cent but we need to take into consideration that he has been with the group for only one [training] session". And we never hide behind this or that player, this or that injury.
'I don't have a problem to arrive at the end of my contract and be free to decide what I want to do and the club free to decide what they want to do'.