The wider Nifty50 of the National Stock Exchange (NSE) once again slipped below the psychologically important 10,000-mark - which was reclaimed on Tuesday - to close lower by 32.15 points, or 0.32 per cent, at 9,984.80 points.
Among the top Sensex losers: Tata Motors dropped 2.3 percent, State Bank of India declined 2 percent, Tata Steel weakened 1.5 percent while Coal India shed 1.4 percent.
The gauge had soared 332.38 points in the previous three sessions. Markets would also be guided by release of domestic news and activities such as release of inflation data, an IPO from GIC, and an economic and advisory council meeting to be held on Wednesday. The MSCI's broadest index of Asia-Pacific shares outside Japan climbed 0.5 per cent to 546.38, a level not seen since December 2007.
China protests US Navy sailing near South China Sea
However, Hua said: "The Chinese government will continue to safeguard its territorial sovereignty and maritime entitlements". A US official said the destroyer Chafee sailed near the Paracel Islands on Tuesday, coming within 16 nautical miles of land.
Extending its rally, the 30-share Sensex was up 104.02 points, or 0.32 per cent, at 32,028.43.
The Nifty was trading at 10,042.70 points in the morning.
Among them, realty index gained the most by 1.07 per cent, followed by oil & gas 1.04 per cent, power 0.78 per cent and infrastructure 0.71 per cent.