Strong winds are hindering the efforts of fire crews.
NASA released some new images Friday of what the fires look like from space while the ISS crew is in low Earth orbit.
One showed the solar array of the space station with California down below, and in the distance, smoke streaming off the coast and into the ocean.
Astronaut Randy Bresnik also shared pictures from the International Space Station after someone asked whether he could see the fires from space.
Carlton Cole says Adrian should start over West Ham's Joe Hart
But we'll have to have a performance similar to get us a result. "I am happy having the two of them". But tactically I think we need to be slightly different to give us a chance.
The images offer a different perspective on the scope of the fires, with most capturing massive plumes of smoke. Yes Faith, unfortunately we can.
Powerful Santa Ana winds fanned the flames.
As multiple wildfires wreak havoc on Southern California, astronauts and satellites are documenting the scene from above.
The fires are being fed by the desiccated remains of lush vegetation that grew during one of the wettest winters on record in California, only to endure a record warm and dry summer.
The photograph below was also taken on December 5 by the Multi Spectral Imager on the European Space Agency's Sentinel-2 satellite. The MSI makes observations in visible, shortwave infrared and near infrared light. Active fires appear orange; the burn scar is brown.