Universal blood test for cancer one step closer

Missouri Gov. Eric Greitens delivers the annual State of the State address to a joint session of the House and Senate Wednesday Jan. 10 2018 in Jefferson City Mo

Universal blood test for cancer one step closer

18, 2018 A simple, cheap blood test to detect colon cancer - even in its early stages - appears highly effective and accurate, new research indicates.

"This test represents the next step in changing the focus of cancer research from late-stage disease to early disease, which I believe will be critical to reducing cancer deaths in the long term", says Vogelstein. Some search for proteins in the blood that show up with malignancy. Be that as it may, these techniques alone don't give dependable outcomes.

Nimgaonkar is a gastroenterologist and medical director of Johns Hopkins University's Center for Bioengineering Innovation and Design, in Baltimore. It joins two strategies into one test.

The team tested the liquid biopsy on people who had already been diagnosed with one of eight cancers: ovarian, liver, stomach, pancreatic, esophageal, colorectal, lung or breast.

The researchers have been trying for decades to develop a test that could predict cancers.

The test has been designed mainly for people over the age of 50, as well as younger people with a family history of cancer.

The test detects so-called "circulating tumor cells" (CTCs).

They likewise took a gander at 812 individuals without disease judgments and discovered only seven of them - under 1 percent - obviously had a false perusing that discovered malignancy.

'The now available screening tests can also be unpleasant, have associated risks and uptake can be low.

"Just like stool tests, this test would not replace diagnostic colonoscopies", he said. Also, that rate could well be lower than the 70 percent normal.

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But it can be like looking for "less than a needle" in a haystack, said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society. "That could spare their life". "This paper is provocative", he says. Professor Gibbs, who also works as an oncologist, said, "We see a lot of people with advanced cancer". For example, if the achievement rate is around 40 percent at distinguishing malignancy, that implies it misses cancers more regularly than it discovers it.

"The last thing you'd want is a test that tells you you might have cancer if you don't", he said. He is anxious that patients will contemplate internally, "Despite the fact that I have this unusual stomach torment that won't leave, I know it's not tumor".

Another issue is that the test comes about discover indications of growth, however frequently neglect to pinpoint which part of the body is influenced.

"We're very, very excited and see this as a first step", said Nickolas Papadopoulos, one of the Hopkins study leaders.

"We are still evaluating the test, and it hasn't been commercialized yet", he said. Recently DNA released from the tumors was being tested. "We're moving farther down the path toward using (a test like this) for screening".

The company's chief executive, Atul Sharan, said USA studies should start this year. The scientists at the Hopkins are now testing their test on tens of thousands of apparently healthy volunteers who are enrolled in the Geisinger Health Plan in Pennsylvania.

On the off chance that that multiyear try succeeds, the researchers will in any case need to exhibit that the test enhances and expands the lives of malignancy patients. "Be that as it may, despite everything I think this is exceptionally helpful data, realizing that something is going on and tail it up".

But Professor Gibbs said they expected the cost to come down over time as the technology progressed and the number of people being tested rose.

As for cost, the researchers estimate the blood test could run less than $500 - comparable to a colonoscopy to screen for colon cancer, Lennon noted.

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