The broadcaster shared a video on his Twitter page in which he revealed he underwent surgery for prostate cancer in January and "it all seemed to go pretty well".
He had gone to the doctor for flu but a health check revealed that his prostate-specific antigen (PSA) levels were high.
In the 12-minute clip, the national treasure said doctors found the cancer in an MRI scan a year ago after he went for a full health check, but luckily he is now on the road to a full recovery.
Stephen - who is married to Elliott Spencer - was offered radiotherapy or surgery to have his prostate removed, but he made a decision to have the eleven lymphnodes removed as well. "The various bits that were taken out were examined and it turned out I had a Gleason score of nine, and considering 10 is the maximum, it was clearly an aggressive little bugger", he said.
"Cancer is a word that rings in your head". And then the next day Tony calls again and he says, 'Oh Stephen, something rather mischievous has showed up.' I was told to have a biopsy ... and the next day I get the results and, yes indeed, there is a cancer there.
He closed the video by saying, "Thank you for listening and watching, and get yourself checked and follow your doctor's advice". But I won't know for sure until my PSA levels are checked and they should be 0 now because I have no prostate.
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"In case you've been wondering why I've been out of the public eye".
He confirmed that the operation was a success, adding: "So far as we know, it's all been got".
"You don't think it to happen to you - cancer is something happens to other people".
He added: "For the moment I am fit and well and happy but I just wanted to let you know because rumors had started to swirl".
Fry, who has previously appeared on Irish soap opera Ros na Rún, said he life was saved by the early intervention.