They can avoid that tense scenario by finding a way through a formidable Atletico defence and clinching not just a shock triumph and a European trophy, but also an immediate place in next season's Champions League group stage. He can turn the game at any moment of the match.
"They have the experience but we've studied our opponents and we'll know how to take them on", he said.
Mandanda warned Griezmann isn't Atletico's only threat, however. Team-mate Saul Niguez believes that only one thing will be on Griezmann's mind. But there's also Diego Costa, Kevin [Gameiro] and Fernando Torres, who could come on at some point.
"I feel sad that I won't be as close as I'd like to the players but we had this situation before, when German took charge against Arsenal", he said.
The France global has been Atletico's top scorer in every season since joining from Real Sociedad in 2014, but a constant stream of transfer stories linking him with clubs from Manchester United to rivals Real Madrid has led to him being booed by his own supporters this season.
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But it was enough for Boston to bamboozle Cleveland in a 108-83 victory that equaled their four-game clash this season at 2-2. The former UCLA standout did not mince words when giving his assessment, referring to Cleveland's defensive effort as "soft".
"The fact we played a day earlier against Guingamp is an advantage". Yes, I feel I can play tomorrow. "We're going to try to remove the last doubts this afternoon, but we should be able to count on everyone". Simeone needs to improve on his record in finals, but his approach will be difference because the expectation is now on his shoulders.
Simeone's side endured agonising defeats to city rivals Real Madrid in the 2014 and 2016 Champions League showpieces but have fond memories of thrashing Athletic Bilbao 3-0 in the 2012 Europa League final in Bucharest. Both teams are very pragmatic and play a similar style. "They have more experience than us, but it's good for us that it'll be decided over one match, that means anything is possible".
"We are full of respect for Atletico, a great Spanish club".
"Those who won the Champions League in 1993 are still heroes because nobody else has done it since", Dimitri Payet told uefa.com.
"We are lucky to be at Marseille, a club with a love affair with European competitions that goes back to the 1990s, and we are all eager to follow in the footsteps of our illustrious predecessors", Garcia said. "It'll be a very hard mission".