He faces treason charges.
He was forced into a waiting police vehicle, registration number, UP 7500 and driven straight to Kasangati police station near his home in Magere.
According to Government spokesperson Ofwono Opondo, Bobi Wine was safely delivered at his home by police.
Security forces had deployed around Entebbe International Airport and the highway linking it to the capital Kampala ahead of his arrival to prevent supporters from greeting him.
"We wish to thank him for cooperating with the police at Entebbe International Airport who provided him with transport, escort and a lead vehicle to his home".
Kyagulanyi, a prominent challenger to long-ruling President Yoweri Museveni, was returning from the United States, where he received treatment for injuries he said were sustained during torture by security forces. "There are 40 million people who need hope so I will go and meet them no matter what", Wine told the Guardian.
On Wednesday, police made it clear in a statement that they would transport the legislator to his home and arrest anybody who welcomed him at the airport or stayed by the roads to catch a glimpse of him. Bobi Wine wrote on social media also adding that none of his family members will pick him but he will instead find them home.
Addressing Bobi Wine's arrest reports, Inspector General of Police (IGP) Martin Okoth Ochola said, "Nobody has arrested Bobi Wine, we are simply escorting him".
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Authorities banned rallies to welcome Ssentamu home.
Ssentamu, who won a national assembly seat past year, faces treason charges over his alleged role in an incident last month in which the president's convoy was pelted with stones.
He denies wrongdoing. His next court appearance is October 1.
The 36-year-old Ssentamu says he is fighting for freedom from oppression and wants longtime President Yoweri Museveni, in power since 1986, to retire. Museveni in turn has accused opposition figures of trying to lure Uganda's large youth population into rioting.
Upon his arrival at Entebbe global airport, the legislator was led to a Police vehicle and driven off to his home, according to an earlier statement by Police spokesperson, SSP Emilian Kayima.
Ssentamu has a big following among the poor and unemployed in urban areas.
Dozens of global musicians have condemned the treatment of the singer, and the European Union parliament and some US senators have urged Ugandan authorities to respect basic human rights.