Latest Isaac tropical storm image from Harry Halstrom, Pond Hill forecaster.
Ireland is expected to endure the worst of the storm, while Wales and the Cornish peninsula will bear its brunt in England.
On the forecast track, Isaac will move over the eastern and central Caribbean Sea during the next few days.
Florence, however, continues to threaten the east coast as a fierce storm that could trigger flooding as far south as Georgia.
Given the lack of deep convection to sustain the cyclone, continual gradual weakening is expected.
Helene, which has been downgraded from a hurricane, is among a glut of tropical storms brewing in the region, with mass evacuations under way in southern U.S. states as Hurricane Florence barrels across Virginia and the Carolinas.
Rainfall amounts of 2 to 4 inches with isolated amounts up to 6 inches over elevated terrain are forecast across Martinique and Guadeloupe.
Jurgen Klopp laughs off Gary Neville's comments about Liverpool
Jurgen Klopp has hit back at pundit Gary Neville after the former Manchester United defender suggested Liverpool should abandon the Champions League to boost their Premier League title hopes.
Isaac was about 220 miles east of Dominica, an island on the eastern rim of the Caribbean.
Isaac was moving west Wednesday afternoon at a speed of nearly 17 miles per hour. A Category 4 hurricane at its strongest, Olivia spent about a week swishing around in the Pacific Ocean without making landfall before it weakened into a tropical storm.
Isaac is expected to produce total rainfall accumulations of two to four inches with isolated amounts up eight inches across Martinique, Dominica, and Guadeloupe, one to two inches with isolated amounts to four inches across Puerto Rico and the southern United States Virgin Islands, with up to an inch anticipated across the remaining Windward and Leeward Islands. Tropical storm conditions are possible within the tropical storm watch area on Thursday.
Wind gusts of up to 65mph are forecast with up to 80mph possible in more exposed areas.
The Met Office also say there is a small chance injuries could occur from large waves and beach material being thrown onto sea fronts.
Swells generated by Isaac will begin to affect portions of the Lesser Antilles this afternoon.