The thousands of Hondurans are making their way through Guatemala, headed toward Mexico and, if they're allowed through, plan to head onward to the US, as the contentious midterm elections approach November 6.
The key questions: Will Mexico let the migrants in?
Tension was palpable in Ciudad Hidalgo, a tiny tropical village in Mexico surrounded by rain forest and banana plantations that borders Tecun Uman in Guatemala, with the two towns separated by a muddy river.
"If these people are really concerned about persecution, fear and death and they want to claim political asylum, they are now out of Honduras". In April, the president did deploy the National Guard to assist at the border, a move previously done by both President George W. Bush and President Barack Obama.
In 2017, the United States sent about $530 million in aid to Guatemala, Honduras, and El Salvador.
Beyond that, this situation catches Mexico at a unusual time.
Launched Saturday from Honduras, the caravan reportedly has grown to more than 4,000 people, including whole families and - in some cases - children traveling without their parents.
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It could reject them completely and ask Rome to rewrite them, an unprecedented step that would formally begin a long dispute. The commission is expected to send a formal letter with its assessment to the Italian government within the next two weeks.
Migrants have been known to cross the river on rafts for years - sometimes encountering authorities along the way, sometimes meeting little resistance as they slipped into Mexico and continued their journey north.
The group chanted: 'We are not smugglers, we are migrants, ' as they reorganized themselves on Friday afternoon.
Mexico's ambassador to Guatemala said his country had made a decision to enforce a policy of "metered entry" in the face of the thousands clamoring to cross.
Participants in a 3,000-strong migrant caravan heading toward the United States have gathered in a park to wait a few more hours for members of the group who are still arriving.
Asked in the Televisa interview whether Mexico was doing Trump's "dirty work", Videgaray said Mexico "defines its migration policy in a sovereign manner" and the country's priority is to protect the migrants and ensure their human rights.
But it's not clear what they will do - if they will physically prevent them from crossing the border or just monitor the situation.
In a series of tweets Thursday morning, Trump accused the governments of Guatemala, Honduras and El Salvador of allowing a large "caravan" of migrants to proceed towards the United States unchecked, and hit out at the Democratic party for opposing his own brand of tough border control.
The Trump administration appears equally pleased with the agreement, with Secretary of State Mike Pompeo praising the Mexican government for its cooperation.