World's first baby born via womb transplant from dead donor

The first successful birth of a child from a womb transplanted from a dead donor in Brazil should give hope to thousands of British women that they can have children, doctors said.

"It enables use of a much wider potential donor population, applies lower costs and avoids live donors' surgical risks", Saso stated.

Six weeks after the uterine transplant, which was performed in 2016, the Brazilian woman started having periods again. The mother is the first in the world to give birth after such a transplant, a feat doctors were not sure would ever be possible.

It said the case involved connecting veins from the donor's uterus with the recipient's veins, as well as linking arteries, ligaments, and vaginal canals.

The transplanted uterus was removed during the procedure, and no anomalies were seen.

"Successful pregnancy, without evidence of any compromise in spite of the uterus (womb) being without oxygen for eight hours before transplant, was unique".

Of this group, one in 500 women have problems with their uterus - due, for example, to a malformation, hysterectomy, or infection - that prevent them from becoming pregnant and carrying a child to term.

But the outcomes and effects of donations from live and deceased donors are yet to be compared.

Since live uterus donors are a limitation, the report shows that uterus transplants from deceased donors are feasible and may open access for all women with uterine problems, without the need for live donors, as is the practice now.

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Previously, there have been 10 other uterus transplants from deceased donors attempted in the US, Czech Republic and Turkey, but this is the first to result in a live birth.

Pregnancy was confirmed 10 days after implantation.

On 15 December 2017, a baby girl weighing 2,550 grams (5.6 pounds) was delivered through Caesarean section. Uterine transplants can sidestep these issues and allow women who otherwise wouldn't be able to have the chance to carry their own pregnancies.

"Up to 15 percent of couples suffer from infertility and every year thousands of women are using gestational carriers in order to conceive", said Dr. Tomer Singer, who directs reproductive endocrinology at Lenox Hill Hospital in New York City.

The current norm for receiving a womb transplant is that the organ would come from a live family member willing to donate it. Those transplants can only be done for women who find a donor, who must undergo a complicated surgery and lengthy recovery, Dr. Tullius said.

The early embryos produced by IVF treatment had been frozen and stored four months before the transplant.

"The results establish proof-of-concept for treating uterine infertility by transplantation from a deceased donor, opening a path to healthy pregnancy for all women with uterine factor infertility, without need of living donors or live donor surgery", Brazilian researchers said in the study published Tuesday in the medical journal The Lancet. For future procedures he hopes to cut down on the time to transplant by removing the uterus before other organs, like the heart and kidneys. Immunosuppression was continued outside of hospital until the birth.

There have been a total of 39 live donor transplants, resulting in 11 live births in the past five years.

At the age of seven months and 20 days, when the case report was written, the baby was breastfeeding and weighed 7.2kg (15lbs 14oz).

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