That game kicks-off just minutes after the final whistle at Selhurst Park, making it all the more vital that City land a psychological blow by going back to the top of the table against Palace.
Ilkay Gundogan told Sky Deutschland that City had not been "brave enough" and made too many "simple mistakes" in a game where Son Heung-min scored the only goal after 78 minutes.
Since then? Full matches merely versus Cardiff, Schalke and Newport.
The midfielder felt it was in keeping with other "nervous" Champions League displays that mean City are not yet a "big team".
"I think there will be some dropped points still".
"With Pep Guardiola, we are witnessing an awesome title race, the two teams play the right way, the managers perform the right way". That's why we made a decision to play a different type of game.
Lightning's Kucherov suspended 1 game for boarding Blue Jackets' Nutivaara
His absence would be another notable one, but there's some optimism he'll play Game 3. However, through two games of the first round Kucherov has yet to record a point.
"Now it doesn't count if this decision was good or not after the game", he began. We didn't want to concede a counter-attack, where they are stronger than us.
Last season, Palace ended City's record 18-game winning run last season but Guardiola's team still amassed 100 points as they cruised to the title.
Chelsea are absolutely desperate for a repeat of the Jose Mourinho-masterminded 2014 win at Anfield that helped derail Liverpool's last title challenge, and that will crank the pressure up in today's later game.
"Unfortunately, we could not score a goal but have a second leg with our fans at home and we'll be in the semi-finals". I do not agree with what Ilkay says.
Asked how we'll approach a game against a team whose Premier League fate has already been sealed, Mauricio replied: "Always with all the respect".
After Palace, City host Tottenham twice in four days in the second leg of their Champions League tie and the Premier League.