United started fast and threatened in the opening two minutes through Marcus Rashford, whose shot clipped the top of the crossbar, and through Scott McTominay, who found himself in space in the penalty area only for his touch to let him down.
Messi made sure there was no memorable Champions League comeback for Manchester United at Camp Nou on Tuesday, scoring two early goals to help Barcelona beat United 3-0 and reach the last-four for the first time in four seasons with a 4-0 aggregate score.
He was slammed by United fans and the local press, with Manchester Evening News giving him a 1/10 rating - the lowest of any player on the pitch. "In the next few years it is going to be a massive effort to get to the level of Barcelona and these sorts of teams".
Barcelona's win against Manchester United has also seen them take another step closer to winning the treble this season, but Messi stressed that the club had to take the rest of the campaign in bitesize pieces. It was the worst draw we could have got.
The first blood score came in the 16th minute of the second leg match at Camp Nou.
Messi then made it 2-0 in the 20th minute when his shot caught out David De Gea, who should have been able to make a routine save.
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"At 2-0 straight after it was game over".
He explained: "You can't make errors in these games. The good thing is we play differently to PSG".
He added Messi's majestic display underlined why is he regarded as the best player in the world alongside Cristiano Ronaldo. We were cold and nervous for the first five minutes.
We were always underdogs but we had to back ourselves and believe.
Barca will enter the semi-finals as one of the favourites to win the Champions League for what would be their sixth title.
"We had a lot of hope for this tie, it was a long time since we have been in the semi-finals and we had a very painful defeat previous year", he said.