"It's clear he'll take no part in the Tour", Brailsford told French television while four time Tour de France victor Froome was being treated at the scene in a parked ambulance.
Dave Brailsford, Ineos team principal, praised Froome's preparation for an attempt at winning his fifth Tour de France title - something he will now be prevented from trying to achieve this year.
The four-time Tour de France victor was hospitalised and will miss July's race after a crash, which happened before the fourth stage of the Critérium du Dauphiné. He has also suffered fractured ribs.
Froome's last major win came at the 2018 Giro where he also fell while doing recon for the opening day time-trial around Jerusalem, suffering early in the three week race before spectacular late rally.
"On behalf of the Team, I would like to commend the treatment he received from the emergency services and all at Roanne Hospital in assessing and stabilising him".
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Britain's four-times victor of the Yellow Jersey was airlifted to hospital with multiple injuries - including a broken leg, broken elbow and fractured ribs - after a crash that shook cycling. "It'll take quite a long time before he races again", Brailsford told French TV.
"Our primary focus now is obviously on ensuring Chris gets the very best possible care, which he will do, so he can recover as soon as possible", said Brailsford. He hit a wall.
"One of our big strengths on this team is coming together in hard moments, and we will ensure we do everything possible to support Chris and his family", he said. Long-time Froome teammate Geraint Thomas is the defending champion.
Chris Froome will miss the Tour de France and the rest of 2019 - after smashing into a wall at 40mph while blowing his nose.
He would have been chasing the victory that would have seen him equal the record five Tour de France wins of Jacques Anquetil, Eddie Merckx, Bernard Hinault and Miguel Indurain.